SCHEMBL24864615

SCHEMBL24864615

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 1/20 0.45
▸ GLP1R P43220 8/20 0.44
▸ ITGB3 P05106 6/20 0.43
▸ ITGA2B P08514 6/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ CTSS P25774 1/20 0.41
▸ CTSK P43235 1/20 0.41
▸ ACE P12821 1/20 0.40
▸ FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27145930 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL27150954 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL27145928 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL31045346 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL21713192 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL21713193 0.90 CAPN1 (0.46) CAPN1GLP1RITGB3ITGA2BMEN1
SCHEMBL13936448 0.86 GLP1R (0.54) CAPN1GLP1RMEN1GAAKMT2A
SCHEMBL13936450 0.86 GLP1R (0.54) CAPN1GLP1RMEN1GAAKMT2A
SCHEMBL30895514 0.85 ALB (0.43) CAPN1GLP1RMEN1GAAKMT2A
SCHEMBL31407837 0.83 MEN1 (0.56) CAPN1ITGB3ITGA2BMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-03-26 — — US disclosed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP disclosed
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-08-08 — — US disclosed
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-07-25 — — US disclosed
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-06-27 — — US disclosed
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-06-27 — — US disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 — — WO disclosed
WO-2023280227-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2023-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME CD74, HACD3, FCGR2A CAPN1 3934/4885GLP1R 1984/4885ITGB3 268/4885
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 CAPN1 2891/4885GLP1R 2279/4885ITGB3 364/4885
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 CAPN1 2891/4885GLP1R 2279/4885ITGB3 364/4885
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 CAPN1 2891/4885GLP1R 2279/4885ITGB3 364/4885
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 CAPN1 2891/4885GLP1R 2279/4885ITGB3 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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