Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.71 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.71 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.71 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | KRAS | P01116 | 2/20 | 0.57 |
| ▸ | DTYMK | P23919 | 4/20 | 0.55 |
| ▸ | NT5E | P21589 | 2/20 | 0.53 |
| ▸ | POLG | P54098 | 1/20 | 0.50 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864701 | 1.00 | POLB (0.75) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL18963993 | 1.00 | POLB (0.75) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL19389402 | 0.96 | POLB (0.76) | POLBP2RY2P2RY4P2RY6FUT5 | |
| Deoxyguanosine Triphosphate SCHEMBL18785123 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| Deoxyguanosine Triphosphate SCHEMBL12729493 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL16699229 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| Deoxyguanosine Triphosphate SCHEMBL2820367 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| Deoxyguanosine Triphosphate SCHEMBL80609 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL3042901 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 | |
| Deoxyguanosine Triphosphate SCHEMBL252797 | 0.94 | POLB (0.81) | POLBP2RY2P2RY4P2RY6FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230010731-A1 | DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230010731-A1 | DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION | POLN, DNTT, NT5C3B | POLB 11/4885P2RY2 544/4885P2RY4 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.