SCHEMBL24865110

SCHEMBL24865110

O=C(c1c(O)c2ccc3ccccc3c2n(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.31
KDM4E B2RXH2 3/20 0.30
ALDH1A1 P00352 2/20 0.30
LMNA P02545 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30171398 0.82 KDM4E (0.44) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL24864764 0.82 KDM4E (0.44) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL27212328 0.80 HTT (0.49) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL30171413 0.80 HTT (0.49) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL24864709 0.78 ALDH1A1 (0.44) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL24864744 0.74 RECQL (0.40) KDM4ETDP1MEN1HTTKMT2A
SCHEMBL24864978 0.70 TRPV1 (0.38) KDM4EEGLN1
SCHEMBL24865290 0.68 LMNA (0.41) ALDH1A1LMNAEGLN1MEN1HPGD
SCHEMBL24864984 0.68 RECQL (0.36) KDM4EALDH1A1LMNATDP1MEN1
SCHEMBL24864724 0.68 MEN1 (0.47) KDM4EALDH1A1LMNAMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed