Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336404 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNADDB1CRBN | |
| SCHEMBL24865084 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL30336260 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL24865606 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNADDB1CRBN | |
| SCHEMBL30336970 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNADDB1CRBN | |
| SCHEMBL24864844 | 0.82 | MAPT (0.46) | ALDH1A1MAPTLMNADDB1CRBN | |
| SCHEMBL30336715 | 0.82 | MAPT (0.46) | ALDH1A1MAPTLMNADDB1CRBN | |
| SCHEMBL31123358 | 0.81 | FLT3 (0.44) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL24865542 | 0.81 | FLT3 (0.44) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL24865699 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |