Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865384 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865640 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865442 | 0.82 | MAPT (0.46) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865211 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| SCHEMBL31123358 | 0.77 | FLT3 (0.44) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865542 | 0.77 | FLT3 (0.44) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865398 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| SCHEMBL24865084 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865209 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24865638 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |