Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | BCL6 | P41182 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336545 | 1.00 | MAPT (0.44) | MAPTBCL6ALDH1A1HTTNCOR2 | |
| SCHEMBL24865579 | 0.88 | ALDH1A1 (0.45) | MAPTBCL6ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30336323 | 0.88 | ALDH1A1 (0.45) | MAPTBCL6ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30336503 | 0.87 | ALDH1A1 (0.48) | MAPTBCL6ALDH1A1HTTNCOR2 | |
| SCHEMBL24865649 | 0.87 | ALDH1A1 (0.48) | MAPTBCL6ALDH1A1HTTNCOR2 | |
| SCHEMBL24865509 | 0.82 | SMN1; SMN2 (0.42) | MAPTBCL6ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24865744 | 0.82 | BCL6 (0.40) | MAPTBCL6ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24865039 | 0.82 | PIK3CA (0.46) | BCL6ALDH1A1HTTSMN1; SMN2TP53 | |
| SCHEMBL24865635 | 0.80 | BCL6 (0.39) | MAPTBCL6ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31123320 | 0.80 | BCL6 (0.39) | MAPTBCL6ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |