SCHEMBL24865255

SCHEMBL24865255

O=C(c1c(O)c2ccc3c4ccccc4sc3c2n(-c2cccc(-c3ccccc3)c2)c1=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.36
RXFP1 Q9HBX9 3/20 0.36
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 6/20 0.35
HDAC6 Q9UBN7 2/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
ALOX5 P09917 1/20 0.33
EGLN1 Q9GZT9 2/20 0.33
PDE10A Q9Y233 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30171448 1.00 MAPT (0.36) MAPTRXFP1MEN1GAAKMT2A
SCHEMBL24864800 0.91 TP53 (0.35) MAPTRXFP1MEN1KMT2ATP53
SCHEMBL24864715 0.91 RECQL (0.37) MAPTRXFP1MEN1KMT2ATP53
SCHEMBL24864714 0.84 PARP14 (0.34) MAPTRXFP1TP53HDAC6TNKS
SCHEMBL24864828 0.83 EGLN1 (0.33) MAPTRXFP1TP53EGLN1
SCHEMBL24864827 0.81 EGLN1 (0.31) EGLN1
SCHEMBL24864826 0.80 TP53 (0.33) MAPTRXFP1TP53
SCHEMBL24864719 0.79 ALDH1A1 (0.40) MAPTRXFP1MEN1KMT2ATP53
SCHEMBL24864991 0.78 RECQL (0.36) MAPTRXFP1MEN1GAAKMT2A
SCHEMBL30171422 0.78 RECQL (0.36) MAPTRXFP1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 MAPT 3174/4885RXFP1 689/4885MEN1 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.