Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123255 | 1.00 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL24865336 | 0.93 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL31123317 | 0.89 | GABRG2 (0.42) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL24865253 | 0.89 | GABRG2 (0.42) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL31123306 | 0.89 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL24864970 | 0.89 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL31123189 | 0.88 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL24865342 | 0.88 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL24865250 | 0.88 | GABRG2 (0.40) | GABRG2GABRB3GABRA5SYKHTR1A | |
| SCHEMBL31123227 | 0.88 | GABRG2 (0.40) | GABRG2GABRB3GABRA5SYKHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |