Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL20543512 | 0.98 | GPR84 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL1932662 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL10958705 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL1931289 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL1932427 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL2848647 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL1068793 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL1931396 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL9501255 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 | |
| SCHEMBL1931514 | 0.87 | LMNA (0.42) | GPR84FFAR1ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376583-A1 | INKJET INK, INK CARTRIDGE, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, AND IMAGE FORMED MATTER | Ricoh Company, Ltd. (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010079670-A1 | INKJET INK, INK CARTRIDGE, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, AND IMAGE FORMED MATTER | RICOH COMPANY, LTD. (JP) | 2010-07-15 | — | — | WO | disclosed |