SCHEMBL2486550

SCHEMBL2486550

C=C(CC(O)CCCC)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.55
TET2 Q6N021 3/20 0.47
TET3 O43151 1/20 0.47
TET1 Q8NFU7 1/20 0.47
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 1/20 0.44
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRM1 Q13255 1/20 0.41
GRM2 Q14416 1/20 0.41
CA2 P00918 1/20 0.41
MAPK1 P28482 1/20 0.41
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629128 0.92 GPR84 (0.67) GPR84TET2FFAR1FFAR4NFKB1
SCHEMBL3517443 0.88 TET2 (0.50) GPR84TET2TET3TET1FFAR1
SCHEMBL613228 0.82 FFAR4 (0.52) GPR84FFAR1FFAR4CA2MAPK1
SCHEMBL9356945 0.82 TET2 (0.48) GPR84TET2TET3TET1GRIK1
SCHEMBL30239202 0.80 TSHR (0.49) GPR84TET2MAPK1
SCHEMBL375217 0.80 ACE2 (0.44) GPR84TET2TET3TET1FFAR1
SCHEMBL2821466 0.79 TET2 (0.42) GPR84TET2TET3TET1GRIK1
Methacrylic Acid SCHEMBL11075211 0.79 TET2 (0.42) GPR84TET2TET3TET1FFAR1
SCHEMBL23777965 0.79 GPR84 (0.59) GPR84FFAR1FFAR4CA2MAPK1
SCHEMBL182717 0.79 TET2 (0.54) GPR84TET2TET3TET1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US claimed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP claimed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US claimed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP claimed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO claimed
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US disclosed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP disclosed
EP-2376053-A1 POROUS POLYMER COATING FOR TOOTH WHITENING McNeil-PPC, Inc. (US) 2011-10-19 EP disclosed
WO-2010080501-A1 POROUS POLYMER COATING FOR TOOTH WHITENING MCNEIL-PPC, INC. (US) 2010-07-15 WO disclosed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US disclosed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP disclosed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO disclosed
EP-0441746-B1 Light-stabilised binding agent for coatings CIBA GEIGY AG (CH) 1995-06-21 EP disclosed
EP-0441746-A2 Light-stabilised binding agent for coatings CIBA-GEIGY AG (CH) 1991-08-14 EP disclosed
US-4515921-A ALKYLPHENYL END GROUPS, BLENDS WITH ELASTOMERS MOBAY CHEMICAL CORPORATION (US) 1985-05-07 US disclosed