Methacrylic Acid

Methacrylic Acid

SCHEMBL11075211

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(CC(O)CCCO)C(=O)O

nearest known ligand 0.42

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.42
TET3 O43151 1/20 0.42
TET1 Q8NFU7 1/20 0.42
GPR84 Q9NQS5 4/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
PTPN1 P18031 1/20 0.35
TGFBR1 P36897 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356945 0.93 TET2 (0.48) TET2TET3TET1GPR84GRIK1
Methacrylic Acid SCHEMBL38659505 0.83 THRB (0.41) TET2GPR84PTPN1TGFBR1FFAR4
Methacrylic Acid SCHEMBL1787281 0.83 THRB (0.41) TET2GPR84PTPN1TGFBR1FFAR4
Methacrylic Acid SCHEMBL8943953 0.81 PTPN1 (0.37) GPR84PTPN1TGFBR1FFAR4ACACB
Methacrylic Acid SCHEMBL9779402 0.81 PTPN1 (0.37) GPR84PTPN1TGFBR1FFAR4ACACB
SCHEMBL346951 0.81 TET2 (0.52) TET2TET3TET1GPR84GRIK1
SCHEMBL2486550 0.79 GPR84 (0.55) TET2TET3TET1GPR84GRIK1
Methacrylic Acid SCHEMBL11876300 0.79 TGFBR1 (0.34) TET2TET3TET1GPR84PTPN1
Methacrylic Acid SCHEMBL27592631 0.79 TGFBR1 (0.34) TET2TET3TET1GPR84PTPN1
Methacrylic Acid SCHEMBL8923925 0.78 THRB (0.39) GPR84PTPN1TGFBR1FFAR4ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4455342-A REINFORCEMENT OF TEXTILES ROHM GMBH (DE) 1984-06-19 US disclosed