Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 12/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336473 | 1.00 | BCL6 (0.45) | BCL6DRD2DRD3KCNH2SMN1; SMN2 | |
| SCHEMBL24865774 | 0.85 | BCL6 (0.45) | BCL6SMN1; SMN2GAATP53 | |
| SCHEMBL31123256 | 0.85 | BCL6 (0.45) | BCL6SMN1; SMN2GAATP53 | |
| SCHEMBL31123270 | 0.84 | BCL6 (0.50) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL24865299 | 0.84 | BCL6 (0.50) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL24865459 | 0.78 | BCL6 (0.46) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL30885111 | 0.78 | BCL6 (0.46) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL24865789 | 0.77 | BCL6 (0.47) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL30336281 | 0.77 | BCL6 (0.47) | BCL6SMN1; SMN2GAAALDH1A1TP53 | |
| SCHEMBL24865620 | 0.76 | DRD2 (0.38) | DRD2DRD3KCNH2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |