Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNH | P51946 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336093 | 1.00 | DRD2 (0.38) | DRD2DRD3KCNH2CCNT1CDK1 | |
| SCHEMBL31053582 | 0.83 | IDO1 (0.44) | DRD2DRD3KCNH2JAK2TBK1 | |
| SCHEMBL25193116 | 0.82 | AR (0.47) | DRD2DRD3KCNH2MAPTAR | |
| SCHEMBL24865618 | 0.80 | CNR2 (0.36) | JAK2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30885112 | 0.80 | CNR2 (0.36) | JAK2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1664150 | 0.78 | SMN1; SMN2 (0.41) | ABL1JAK2TBK1MEN1ALDH1A1 | |
| SCHEMBL25042072 | 0.78 | HRH3 (0.47) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL31053626 | 0.76 | CCNA2 (0.41) | DRD2DRD3KCNH2CCNA2CDK2 | |
| SCHEMBL25193652 | 0.76 | CCNA2 (0.41) | DRD2DRD3KCNH2CCNA2CDK2 | |
| SCHEMBL24865745 | 0.76 | MAPK10 (0.44) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |