Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 5/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865754 | 0.78 | LRRK2 (0.32) | LRRK2PSMD14USP2MMP2P2RX7 | |
| SCHEMBL24865751 | 0.71 | FGFR3 (0.39) | LRRK2 | |
| SCHEMBL24865829 | 0.69 | CSF1R (0.35) | PSMD14USP2MMP2P2RX7 | |
| SCHEMBL30336250 | 0.69 | TRPV1 (0.47) | LRRK2PIK3CATTKDCLK1 | |
| SCHEMBL24864913 | 0.69 | TRPV1 (0.47) | LRRK2PIK3CATTKDCLK1 | |
| SCHEMBL24865544 | 0.67 | BCL6 (0.35) | LRRK2ALK | |
| SCHEMBL24864955 | 0.66 | KDM4E (0.36) | LRRK2SYKALK | |
| SCHEMBL24865761 | 0.63 | JAK2 (0.33) | LRRK2SYK | |
| SCHEMBL30336418 | 0.61 | TRPV1 (0.47) | LRRK2PIK3CADCLK1 | |
| SCHEMBL30336228 | 0.61 | TRPV1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |