Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 14/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865126 | 0.78 | TNIK (0.39) | FGFR3KCNH2FGFR1FGFR2FGFR4 | |
| SCHEMBL24865544 | 0.76 | BCL6 (0.35) | LRRK2EGFRKDM4EMAPT | |
| SCHEMBL24865437 | 0.75 | BCL6 (0.38) | FGFR3KCNH2EGFRKDM4EMAPT | |
| SCHEMBL24864955 | 0.74 | KDM4E (0.36) | LRRK2EGFRKDM4EMAPT | |
| SCHEMBL24865335 | 0.74 | KIT (0.35) | FGFR3KCNH2EGFRKDM4EMAPT | |
| SCHEMBL24865140 | 0.73 | GABRG2 (0.46) | FGFR3KCNH2FGFR1FGFR2FGFR4 | |
| SCHEMBL30885129 | 0.73 | GABRG2 (0.46) | FGFR3KCNH2FGFR1FGFR2FGFR4 | |
| SCHEMBL31123225 | 0.73 | IGF1R (0.39) | FGFR3KCNH2FGFR1FGFR2FGFR4 | |
| SCHEMBL24865175 | 0.73 | IGF1R (0.39) | FGFR3KCNH2FGFR1FGFR2FGFR4 | |
| SCHEMBL24865747 | 0.71 | LRRK2 (0.37) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |