Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865829 | 0.82 | CSF1R (0.35) | PSMD14USP2MMP2P2RX7 | |
| SCHEMBL24865747 | 0.78 | LRRK2 (0.37) | LRRK2PSMD14USP2MMP2P2RX7 | |
| SCHEMBL24865317 | 0.75 | GAK (0.36) | — | |
| SCHEMBL24865544 | 0.73 | BCL6 (0.35) | LRRK2 | |
| SCHEMBL24865611 | 0.69 | BRD4 (0.33) | LRRK2 | |
| SCHEMBL24865444 | 0.67 | DRD4 (0.48) | — | |
| SCHEMBL30336937 | 0.65 | DRD2 (0.38) | P2RX7 | |
| SCHEMBL24864884 | 0.65 | DRD2 (0.38) | P2RX7 | |
| SCHEMBL25041817 | 0.62 | MAPT (0.48) | — | |
| SCHEMBL25041636 | 0.62 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |