Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812110 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL4028312 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL6247529 | 0.83 | CAD (0.43) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL22207692 | 0.83 | KDM4E (0.39) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064309 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064029 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064041 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL13611400 | 0.81 | KDM4E (0.41) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL5808266 | 0.80 | TGFBR1 (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL4659641 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280280-A1 | FUSED-RING COMPOUND THAT ACTS AS KRAS G12D INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-01-12 | — | — | WO | disclosed |
| CN-104710324-B | A kind of method synthesizing scheme for lacosamide | 华润双鹤药业股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104710324-A | Lacosamide synthesis method | CHINA RESOURCES DOUBLE CRANE PHARMACEUTICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |