SCHEMBL24866458

SCHEMBL24866458

COc1cccc(Br)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.88

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.88
KAT6A Q92794 20/20 0.88
KAT6B Q8WYB5 14/20 0.88
KAT5 Q92993 14/20 0.88
KAT8 Q9H7Z6 14/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802418 0.94 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26969637 0.90 KAT7 (0.82) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30680847 0.90 KAT7 (0.82) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802430 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22828463 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL32681126 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29490376 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30637010 0.90 KAT7 (0.92) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817397 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817403 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280182-A1 COMPOUND SERVING AS KAT6 INHIBITOR 杭州英创医药科技有限公司 2023-01-12 WO disclosed