SCHEMBL29490376

SCHEMBL29490376

COc1cccc(O)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 1.00
▸ KAT6A Q92794 20/20 1.00
▸ KAT6B Q8WYB5 13/20 0.88
▸ KAT5 Q92993 13/20 0.88
▸ KAT8 Q9H7Z6 13/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802430 1.00 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802418 0.94 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802503 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26165867 0.90 KAT7 (0.85) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866458 0.90 KAT7 (0.88) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22828463 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL32681126 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30637010 0.90 KAT7 (0.92) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817397 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866486 0.88 KAT7 (0.89) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364672-B Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2024-09-06 — — CN disclosed
EP-3986890-A1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES Pfizer Inc. (US) 2022-04-27 — — EP disclosed
CN-114364672-A Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2022-04-15 — — CN disclosed
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