Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867214 | 0.88 | RAB9A (0.43) | RAB9AMAPK1ACACBPTGS1PTGS2 | |
| SCHEMBL24866885 | 0.87 | RAB9A (0.52) | RAB9AMAPK1CCNA2CDK2ACACB | |
| SCHEMBL30130169 | 0.87 | RAB9A (0.52) | RAB9AMAPK1CCNA2CDK2ACACB | |
| SCHEMBL24867244 | 0.82 | RAB9A (0.44) | RAB9AMAPK1CCNA2CDK2CDK5 | |
| SCHEMBL30130213 | 0.80 | SYK (0.40) | RAB9AMAPK1 | |
| SCHEMBL30130219 | 0.80 | SYK (0.40) | RAB9AMAPK1 | |
| SCHEMBL30130179 | 0.80 | RAB9A (0.49) | RAB9AMAPK1CDK2ACACBALOX5 | |
| SCHEMBL24866862 | 0.80 | HDAC3 (0.48) | RAB9AMAPK1CDK2PTGS1PTGS2 | |
| SCHEMBL24867304 | 0.79 | RAB9A (0.40) | RAB9AMAPK1CDK2PTGS1PTGS2 | |
| SCHEMBL24867179 | 0.79 | MAPK1 (0.37) | RAB9AMAPK1CDK2ACACBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |