Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 5/20 | 0.40 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866885 | 1.00 | RAB9A (0.52) | RAB9AAKT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24867214 | 0.87 | RAB9A (0.43) | RAB9AAKT1CYP2C9MAPK1ACACB | |
| SCHEMBL24867148 | 0.87 | RAB9A (0.40) | RAB9ACYP2C9MAPK1ACACBCCNA2 | |
| SCHEMBL24867228 | 0.87 | AKT1 (0.46) | RAB9AAKT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24867276 | 0.84 | RAB9A (0.46) | RAB9ACYP1A2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL24866862 | 0.79 | HDAC3 (0.48) | RAB9ACYP2C9ALDH1A1MAPK1CDK2 | |
| SCHEMBL24866909 | 0.79 | AKT1 (0.42) | RAB9AAKT1 | |
| SCHEMBL24867244 | 0.78 | RAB9A (0.44) | RAB9AALDH1A1MAPK1CCNA2CDK2 | |
| SCHEMBL24867304 | 0.78 | RAB9A (0.40) | RAB9AALDH1A1MAPK1CDK2 | |
| SCHEMBL24867240 | 0.78 | BRAF (0.42) | RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366724-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ Biohub SF, LLC (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |