Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 5/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 2/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867308 | 0.88 | PRKAA2 (0.42) | WNT3APORCN | |
| SCHEMBL24867284 | 0.87 | WNT3A (0.43) | RAB9AWNT3AMKNK1 | |
| SCHEMBL24867276 | 0.87 | RAB9A (0.46) | GPR55PCSK9RAB9ACYP2A6MKNK1 | |
| SCHEMBL24867309 | 0.83 | ACACB (0.44) | WNT3AFLT3 | |
| SCHEMBL12413787 | 0.82 | MKNK1 (0.61) | RAB9ACYP2A6MKNK1MKNK2CYP2D6 | |
| SCHEMBL24866935 | 0.80 | RAB9A (0.48) | RAB9A | |
| SCHEMBL24867283 | 0.79 | AKT1 (0.40) | RAB9AMKNK1 | |
| SCHEMBL24867310 | 0.79 | PANK3 (0.43) | — | |
| SCHEMBL24867268 | 0.74 | CHEK1 (0.49) | RAB9AWNT3A | |
| SCHEMBL24866885 | 0.74 | RAB9A (0.52) | RAB9ACCNKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |