Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869074 | 0.83 | RECQL (0.38) | RECQLPTGES2 | |
| SCHEMBL24869039 | 0.78 | RECQL (0.44) | RECQLSLC6A4 | |
| SCHEMBL24869045 | 0.77 | RECQL (0.41) | RECQLMPOSLC6A4KDM4EALDH1A1 | |
| SCHEMBL24869052 | 0.77 | RECQL (0.38) | RECQLMPOSLC6A4 | |
| SCHEMBL12859014 | 0.74 | RECQL (0.43) | RECQLALDH1A1GAAHSD17B10 | |
| SCHEMBL24869051 | 0.74 | FLT3 (0.42) | RECQLALDH1A1 | |
| SCHEMBL24869050 | 0.73 | RECQL (0.46) | RECQL | |
| SCHEMBL9412115 | 0.72 | CTSL (0.40) | CTSLKDM4EGAAALOX15 | |
| SCHEMBL14577239 | 0.70 | RECQL (0.44) | RECQLKDM4EALDH1A1GAA | |
| SCHEMBL10105643 | 0.69 | AR (0.39) | RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |