Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869052 | 0.83 | RECQL (0.38) | RECQLMPOSLC6A4 | |
| SCHEMBL24869051 | 0.81 | FLT3 (0.42) | RECQLALDH1A1TDO2 | |
| SCHEMBL24869050 | 0.77 | RECQL (0.46) | RECQLGABRA1GABRG2GABRB3LMNA | |
| SCHEMBL24869044 | 0.77 | RECQL (0.38) | RECQLALDH1A1KDM4EMPOSLC6A4 | |
| SCHEMBL24869074 | 0.77 | RECQL (0.38) | RECQL | |
| SCHEMBL24869039 | 0.74 | RECQL (0.44) | RECQLLMNASLC6A4 | |
| SCHEMBL12859014 | 0.74 | RECQL (0.43) | RECQLALDH1A1LMNAKCNH3GAA | |
| SCHEMBL5225550 | 0.73 | SHMT2 (0.44) | PIK3CAALDH1A1LMNAKDM4ECYP2C19 | |
| SCHEMBL11994359 | 0.73 | ACE2 (0.41) | RECQLGABRA1GABRG2GABRB3LMNA | |
| Hydrochloric Acid SCHEMBL5398554 | 0.72 | PIK3CA (0.54) | PIK3CAALDH1A1LMNAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |