Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236878 | 0.84 | PTGS1 (0.37) | NOTUMHRH4RECQLIDO1PDE2A | |
| SCHEMBL23195508 | 0.82 | NOTUM (0.34) | NOTUMHRH4RECQLIDO1PDE2A | |
| SCHEMBL24869047 | 0.81 | ALDH1A1 (0.39) | RECQLPDE2ADPP4TRPA1LMNA | |
| SCHEMBL4547922 | 0.80 | NOTUM (0.44) | NOTUMRECQLIDO1PDE2ADPP4 | |
| SCHEMBL10623219 | 0.78 | GAA (0.36) | NOTUMTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL17574081 | 0.78 | S1PR1 (0.32) | RECQLIDO1 | |
| SCHEMBL31409922 | 0.72 | IDO1 (0.46) | IDO1TRPA1SLC6A2ALDH1A1 | |
| SCHEMBL16579371 | 0.72 | NR3C1 (0.35) | IDO1PDE2AHTR2BALDH1A1CYP1A2 | |
| SCHEMBL17280550 | 0.72 | PTGS1 (0.37) | HRH4RECQLSLC6A2ALDH1A1CYP1A2 | |
| SCHEMBL8387655 | 0.72 | ALDH1A1 (0.42) | RECQLIDO1LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |