Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909750 | 0.87 | ALOX5AP (0.39) | ALOX5APFEN1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25484238 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9908241 | 0.81 | HRH4 (0.45) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9918378 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2AL3MBTL1AR | |
| SCHEMBL18929928 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL3066192 | 0.78 | ALOX5AP (0.46) | ALOX5APFEN1ALDH1A1GPBAR1MKNK2 | |
| SCHEMBL9945958 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL25487019 | 0.76 | POLB (0.51) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL24869064 | 0.75 | ALDH1A1 (0.44) | ALOX5APFEN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL24869054 | 0.75 | CYP1A2 (0.42) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |