Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908241 | 0.87 | HRH4 (0.45) | ALDH1A1SMN1; SMN2NPBWR1MCHR1RXRA | |
| SCHEMBL29257300 | 0.87 | HTR2C (0.44) | ALDH1A1SMN1; SMN2NPBWR1MCHR1HTR2C | |
| SCHEMBL29257299 | 0.87 | HTR2C (0.44) | ALDH1A1SMN1; SMN2NPBWR1MCHR1HTR2C | |
| SCHEMBL9945953 | 0.86 | HTR2A (0.46) | ALDH1A1HTR2CHTR2BHTR2AKDM4E | |
| SCHEMBL24869054 | 0.85 | CYP1A2 (0.42) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL24869064 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL18929928 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2NPBWR1MCHR1HTR2A | |
| SCHEMBL9946027 | 0.81 | KMT2A (0.48) | ALDH1A1SMN1; SMN2NPBWR1MCHR1RXRA | |
| SCHEMBL15086403 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL25600572 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPBWR1MCHR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885SMN1; SMN2 3273/4885NPBWR1 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.