Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797207 | 0.79 | SIGMAR1 (0.47) | CHRNB2CHRNA4SIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL29526300 | 0.76 | PDE3B (0.54) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL26460757 | 0.76 | CHRNB2 (0.38) | CHRNB2CHRNA4SIGMAR1PDE3BPDE3A | |
| SCHEMBL477609 | 0.76 | PDE3B (0.54) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL2362200 | 0.74 | PDE3B (0.53) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL28939689 | 0.74 | PDE3B (0.38) | CHRNB2CHRNA4SIGMAR1PDE3BPDE3A | |
| Bromide SCHEMBL28736604 | 0.73 | PDE3B (0.37) | CHRNB2CHRNA4SIGMAR1PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL6217638 | 0.68 | MAPT (0.54) | GAAMAPT | |
| Hydrochloric Acid SCHEMBL30989577 | 0.68 | MAPT (0.54) | GAAMAPT | |
| SCHEMBL2810679 | 0.67 | CDK2 (0.45) | GAAMAPTIDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230008362-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230008362-A1 | COMBINATIONS | WEE2, WEE1, BCL2 | CHRNB2 4681/4885CHRNA4 4876/4885SIGMAR1 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.