Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.64 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.64 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.61 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.61 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.61 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.61 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.61 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.61 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.61 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 3/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344128 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL17333675 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL17333638 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL15540039 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL23221125 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL21265466 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL17333639 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL21265421 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL22647782 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 | |
| SCHEMBL12992106 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2ATP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230009312-A1 | Androstane Derivatives with Activity as Pure or Predominantly Pure Stimulators of SERCA2a for the Treatment of Heart Failure. | WINDTREE THERAPEUTICS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230009312-A1 | Androstane Derivatives with Activity as Pure or Predominantly Pure Stimulators of SERCA2a for the Treatment of Heart Failure. | ATP2A1, ATP2A2, ATP2A3 | CYP19A1 27/4885AKR1B10 577/4885AKR1B1 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.