Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679904 | 1.00 | PKM (0.71) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876742 | 0.96 | PKM (0.76) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876755 | 0.91 | MEN1 (0.69) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876679 | 0.89 | PKM (0.66) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL31679949 | 0.89 | MEN1 (0.63) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876027 | 0.89 | MEN1 (0.63) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL31679847 | 0.88 | KMT2A (0.66) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876631 | 0.88 | KMT2A (0.66) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL24876680 | 0.86 | LMNA (0.66) | PKMMEN1KMT2ALMNATHRB | |
| SCHEMBL31679810 | 0.86 | LMNA (0.73) | PKMMEN1KMT2ALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |