Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211023 | 1.00 | LMNA (0.55) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL23493830 | 0.85 | MEN1 (0.67) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL31307838 | 0.85 | MEN1 (0.67) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL31680017 | 0.84 | MAPT (0.53) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL31679873 | 0.84 | MAPT (0.53) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL24875965 | 0.84 | MAPT (0.53) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL24876376 | 0.84 | MAPT (0.53) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL24876366 | 0.83 | MEN1 (0.58) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL24875967 | 0.83 | THRB (0.53) | MAPTATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24876227 | 0.83 | MAPT (0.50) | LMNAMAPTATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |