Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 18/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 15/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 15/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 15/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 15/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 15/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876155 | 0.73 | GRIN1 (0.49) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973354 | 0.71 | GRIN1 (0.67) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL24875986 | 0.68 | GRIN2D (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7786608 | 0.68 | GRIN2D (0.65) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7784266 | 0.67 | GRIN2D (0.69) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7346405 | 0.67 | GRIN2D (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7786519 | 0.67 | GRIN2D (0.72) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973771 | 0.66 | GRIN1 (0.68) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL121942 | 0.65 | GRIN2D (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL463564 | 0.65 | GRIN2D (0.70) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |