Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 4/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679956 | 1.00 | THRB (0.56) | THRBMEN1KMT2ALMNAPGAM1 | |
| SCHEMBL24876294 | 0.85 | MAPT (0.49) | THRBMEN1KMT2ALMNAPKM | |
| SCHEMBL31679831 | 0.85 | MAPT (0.49) | THRBMEN1KMT2ALMNAPKM | |
| SCHEMBL31680055 | 0.84 | THRB (0.76) | THRBMEN1KMT2ALMNAPKM | |
| SCHEMBL24876645 | 0.84 | THRB (0.76) | THRBMEN1KMT2ALMNAPKM | |
| SCHEMBL24876665 | 0.83 | THRB (0.57) | THRBMEN1KMT2ALMNAPGAM1 | |
| SCHEMBL31679859 | 0.83 | THRB (0.57) | THRBMEN1KMT2ALMNAPGAM1 | |
| SCHEMBL24876158 | 0.81 | THRB (0.56) | THRBMEN1KMT2ALMNAPGAM1 | |
| SCHEMBL31680049 | 0.81 | THRB (0.56) | THRBMEN1KMT2ALMNAPGAM1 | |
| SCHEMBL24876125 | 0.81 | MOGAT2 (0.58) | THRBMEN1KMT2ALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |