Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | SGK1 | O00141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876158 | 1.00 | THRB (0.56) | THRBLMNACDK1CCNB1CCNA2 | |
| SCHEMBL31679837 | 0.88 | LMNA (0.58) | THRBLMNAMEN1KMT2ACA1 | |
| SCHEMBL31679859 | 0.86 | THRB (0.57) | THRBLMNAMEN1KMT2ACA1 | |
| SCHEMBL24876665 | 0.86 | THRB (0.57) | THRBLMNAMEN1KMT2ACA1 | |
| SCHEMBL24876391 | 0.85 | LMNA (0.58) | THRBLMNACDK1CCNB1CCNA2 | |
| SCHEMBL31679800 | 0.85 | LMNA (0.58) | THRBLMNACDK1CCNB1CCNA2 | |
| SCHEMBL24876645 | 0.85 | THRB (0.76) | THRBLMNAMEN1KMT2AIDH1 | |
| SCHEMBL31680055 | 0.85 | THRB (0.76) | THRBLMNAMEN1KMT2AIDH1 | |
| SCHEMBL24876314 | 0.84 | MAPT (0.52) | THRBLMNAMEN1KMT2AIDH1 | |
| SCHEMBL31679967 | 0.84 | MAPT (0.52) | THRBLMNAMEN1KMT2AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |