Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48891 | 0.96 | EGLN1 (0.37) | EGLN1TSHRLTA4HADRA1AMAOA | |
| SCHEMBL2486025 | 0.88 | PRMT1 (0.42) | EGLN1ADRA1APRMT1EPHX2 | |
| SCHEMBL2483730 | 0.87 | TSHR (0.39) | TSHRLTA4HADRA1APOLBMAPK1 | |
| SCHEMBL139047 | 0.85 | TSHR (0.42) | TSHRADRA1APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL23293754 | 0.85 | RECQL (0.42) | TSHRMAOAMAOBALDH1A1LMNA | |
| SCHEMBL12757074 | 0.85 | PAOX (0.33) | MAOAMAOBMAPK1LMNARECQL | |
| SCHEMBL13757930 | 0.83 | MAOA (0.49) | MAOAMAOBLMNA | |
| Succinic Acid SCHEMBL8153802 | 0.82 | PAOX (0.39) | TSHRADRA1APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL22229464 | 0.81 | RECQL (0.40) | TSHRMAOAMAOBALDH1A1LMNA | |
| SCHEMBL17374807 | 0.80 | MAOA (0.46) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379118-B1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GEN ELECTRIC (US) | 2017-10-18 | — | — | EP | claimed |
| US-20140147387-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2014-05-29 | — | — | US | claimed |
| US-8728529-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2014-05-20 | — | — | US | claimed |
| US-8574549-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2013-11-05 | — | — | US | claimed |
| US-20100166664-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | US | claimed |
| US-20100166665-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | US | claimed |
| CN-107029250-B | Nanoparticle contrast agents for diagnostic imaging | 通用电气健康护理有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-2379118-B1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GEN ELECTRIC (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-2379118-B1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GEN ELECTRIC (US) | 2017-10-18 | — | — | EP | disclosed |
| US-9585974-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| US-9585974-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160296641-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GE HEALTHCARE LIMITED (GB) | 2016-10-13 | — | — | US | disclosed |
| US-20160296641-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GE HEALTHCARE LIMITED (GB) | 2016-10-13 | — | — | US | disclosed |
| US-8574549-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2013-11-05 | — | — | US | disclosed |
| US-8574549-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2013-11-05 | — | — | US | disclosed |
| EP-2379118-A2 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | General Electric Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010076237-A2 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100166664-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100166665-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100166666-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296641-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | CD47, CD63, MACO1 | EGLN1 2400/4885TSHR 1547/4885LTA4H 3062/4885 |
| US-20140147387-A1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | CD47, CD63, MACO1 | EGLN1 2400/4885TSHR 1547/4885LTA4H 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.