Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679924 | 1.00 | LMNA (0.57) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679829 | 0.89 | LMNA (0.71) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876106 | 0.85 | LMNA (0.66) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679807 | 0.85 | LMNA (0.61) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876749 | 0.85 | LMNA (0.61) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31680019 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679867 | 0.79 | LMNA (0.75) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876095 | 0.78 | LMNA (0.69) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876094 | 0.77 | LMNA (0.64) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876736 | 0.76 | KMT2A (0.63) | LMNAMEN1KMT2APKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |