Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876749 | 1.00 | LMNA (0.61) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL31679838 | 0.91 | KMT2A (0.63) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL24876736 | 0.91 | KMT2A (0.63) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL31679829 | 0.86 | LMNA (0.71) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL24876625 | 0.85 | LMNA (0.57) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL31679924 | 0.85 | LMNA (0.57) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL24876106 | 0.83 | LMNA (0.66) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL31680056 | 0.81 | MEN1 (0.60) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL31680019 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL24876742 | 0.80 | PKM (0.76) | LMNAMEN1KMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |