Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | BCHE | P06276 | 5/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414451 | 0.78 | BCHE (0.46) | NPC1RAB9AACHEBCHECHRM2 | |
| SCHEMBL2482378 | 0.77 | — | — | |
| SCHEMBL419503 | 0.75 | ACHE (0.52) | PRNPMAPTNPC1ACHEBCHE | |
| SCHEMBL417570 | 0.74 | ACHE (0.50) | ACHEBCHECHRM2CHRM1KMT2A | |
| SCHEMBL412492 | 0.74 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2ALMNAHTT | |
| SCHEMBL2486398 | 0.72 | PRNP (0.36) | PRNPMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL413023 | 0.71 | ACHE (0.52) | NPC1RAB9AACHEBCHEALDH1A1 | |
| SCHEMBL413455 | 0.71 | ACHE (0.54) | ACHEBCHECHRM2CHRM1KMT2A | |
| SCHEMBL415638 | 0.68 | ACHE (0.56) | ACHEBCHECHRM2CHRM1KMT2A | |
| SCHEMBL414416 | 0.68 | ACHE (0.48) | MAPTNPC1RAB9AACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |