Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934263 | 0.84 | ALDH1A1 (0.38) | CA12CA1CA2CA4CA6 | |
| SCHEMBL20439335 | 0.75 | ERN1 (0.34) | CA12CA1CA2CA4CA6 | |
| SCHEMBL13363108 | 0.75 | CYP3A4 (0.39) | — | |
| SCHEMBL24305375 | 0.75 | TSHR (0.32) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10992080 | 0.72 | ALDH1A1 (0.39) | CA12CA1CA2CA4CA6 | |
| SCHEMBL21230379 | 0.71 | ALOX5AP (0.36) | CA2CA4 | |
| SCHEMBL19914812 | 0.71 | HTR2A (0.33) | — | |
| SCHEMBL239457 | 0.70 | PTGER4 (0.43) | CA12CA1CA2CA4CA6 | |
| SCHEMBL31387674 | 0.70 | PTGER4 (0.43) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10990726 | 0.70 | ALDH1A1 (0.36) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |