Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519035 | 0.89 | CHRNB2 (0.69) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6438848 | 0.89 | CHRNB2 (0.69) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4740245 | 0.88 | CHRNB2 (0.65) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21356921 | 0.88 | CHRNB2 (0.65) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7284737 | 0.88 | HDAC1 (0.54) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21356920 | 0.88 | CHRNB2 (0.65) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL38659045 | 0.88 | CHRND (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL12324830 | 0.86 | CHRNB2 (0.69) | FAAHPSMB5CTSBCHRNB2CHRNB4 | |
| SCHEMBL16247369 | 0.86 | CHRNB2 (0.69) | FAAHPSMB5CTSBCHRNB2CHRNB4 | |
| SCHEMBL25497019 | 0.86 | FAAH (0.60) | FAAHPSMB5CTSBHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283434-A9 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023283434-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |