Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | HTR5A | P47898 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23987135 | 0.83 | HTR2C (0.46) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL22303469 | 0.83 | HTR2C (0.46) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL27460012 | 0.78 | HTR2C (0.38) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL23508701 | 0.75 | HTR2C (0.45) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL25707304 | 0.75 | HTR2C (0.45) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL4484620 | 0.75 | HTR2A (0.41) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| Hydrochloric Acid SCHEMBL25347445 | 0.74 | HTR2C (0.44) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| Hydrochloric Acid SCHEMBL30486474 | 0.74 | HTR2C (0.44) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| Hydrochloric Acid SCHEMBL30486634 | 0.74 | HTR2C (0.44) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 | |
| SCHEMBL22303537 | 0.74 | HTR2C (0.38) | HTR2CHTR2BSIGMAR1HTR1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |