Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569311 | 0.86 | DAO (0.44) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL30569314 | 0.86 | DAO (0.44) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL6984148 | 0.83 | DAO (0.52) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL25024180 | 0.81 | DAO (0.42) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL19325274 | 0.79 | DAO (0.43) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL25799818 | 0.79 | DAO (0.43) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL24879828 | 0.78 | DAO (0.40) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL25054107 | 0.76 | DAO (0.41) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL20204799 | 0.76 | DAO (0.41) | DAOMCL1NAPRTAURKAAURKB | |
| SCHEMBL18800357 | 0.76 | DAO (0.41) | DAOMCL1NAPRTAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120476110-B | Nitrogen-containing heterocyclic derivative inhibitor, preparation method and application thereof | SHANGHAI HANSOH BIOMEDICAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119384410-A | Deuterated terpyridyl dione compound or salt thereof, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-4219463-B1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN SALUBRIS PHARM CO LTD (CN) | 2025-01-15 | — | — | EP | disclosed |
| WO-2025007915-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119264042-A | Cyclopentane derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-119176794-A | Heterocyclic compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118908960-A | Nitrogen-containing heteroaryl compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118525005-A | Polycyclic derivative containing pyridine, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20240166627-A1 | Terpyridinedione compound or salt thereof, and preparation method and application thereof | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-23 | — | — | US | disclosed |
| EP-4367099-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-4219463-A1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023134764-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-11685719-B2 | Pyridinone MK2 inhibitors and uses thereof | XINTHERA, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685719-B2 | Pyridinone MK2 inhibitors and uses thereof | XINTHERA, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230053465-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2023016535-A1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016535-A1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2023283338-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283338-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053465-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | ENPP2, PLP2, PDXK | DAO 3021/4885MCL1 1522/4885NAPRT 625/4885 |
| US-20240166627-A1 | Terpyridinedione compound or salt thereof, and preparation method and application thereof | TNF, MAPKAPK2, MAPK1 | DAO 2280/4885MCL1 3371/4885NAPRT 777/4885 |
| US-11685719-B2 | Pyridinone MK2 inhibitors and uses thereof | ENPP2, PLP2, PDXK | DAO 3021/4885MCL1 1522/4885NAPRT 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.