Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15360079 | 0.78 | SMPD3 (0.44) | SMPD3NCF1CRHR1ADORA2AADORA1 | |
| SCHEMBL24896141 | 0.76 | SMPD3 (0.42) | SMPD3NCF1CRHR1MEN1KMT2A | |
| SCHEMBL1687064 | 0.76 | SLC6A2 (0.31) | MEN1KMT2A | |
| SCHEMBL22996100 | 0.73 | MEN1 (0.43) | NCF1MEN1KMT2A | |
| SCHEMBL22133199 | 0.73 | SMPD3 (0.38) | SMPD3NCF1ADORA2AADORA1 | |
| SCHEMBL22605364 | 0.73 | SMPD3 (0.38) | SMPD3NCF1CRHR1 | |
| SCHEMBL1686823 | 0.65 | KDM4E (0.43) | MEN1KMT2A | |
| SCHEMBL11926725 | 0.65 | LMNA (0.40) | MEN1KMT2A | |
| SCHEMBL26948614 | 0.63 | BRD9 (0.35) | SMPD3MAT2A | |
| SCHEMBL25946592 | 0.63 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283434-A9 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023069495-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023283434-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |