Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487269 | 0.92 | PTGDR2 (0.51) | PTGDR2NPC1PKMRAB9AGRM5 | |
| SCHEMBL2489821 | 0.85 | PTGDR2 (0.69) | PTGDR2NPC1PKMRAB9AGRM5 | |
| SCHEMBL2489689 | 0.84 | PTGDR2 (0.62) | PTGDR2NPC1RAB9A | |
| SCHEMBL2487326 | 0.84 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL2492651 | 0.84 | PTGDR2 (0.56) | PTGDR2NPC1PKMRAB9AGRM5 | |
| SCHEMBL2490747 | 0.83 | PTGDR2 (0.61) | PTGDR2GRM5 | |
| SCHEMBL2489822 | 0.83 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL2493195 | 0.83 | PTGDR2 (0.45) | PTGDR2GRM5 | |
| SCHEMBL2131594 | 0.82 | PTGDR2 (0.75) | PTGDR2 | |
| SCHEMBL17818038 | 0.81 | PTGDR2 (0.60) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |