Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491650 | 0.88 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL2492872 | 0.84 | PTGDR2 (0.50) | PTGDR2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL2489660 | 0.83 | KCNQ3 (0.44) | PTGDR2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL2487972 | 0.83 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL2132020 | 0.82 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL2489639 | 0.82 | PTGDR2 (0.45) | PTGDR2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL2493195 | 0.81 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL17818033 | 0.81 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL1569811 | 0.78 | PTGDR2 (0.69) | PTGDR2 | |
| SCHEMBL2489044 | 0.78 | PTGDR2 (0.49) | PTGDR2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |