⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24880387 | 0.81 | — | — | |
| SCHEMBL24880106 | 0.72 | — | — | |
| SCHEMBL24879802 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL24879798 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL23033181 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL24880104 | 0.67 | P2RX7 (0.31) | — | |
| SCHEMBL7904107 | 0.67 | KMT2A (0.35) | — | |
| SCHEMBL24880130 | 0.67 | — | — | |
| SCHEMBL25104385 | 0.64 | HRH3 (0.33) | — | |
| SCHEMBL26299381 | 0.62 | RIPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |