Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879918 | 0.90 | WDR5 (0.35) | WDR5NPC1LMNAGAARAB9A | |
| SCHEMBL24880103 | 0.89 | FGFR4 (0.35) | KCNH2WDR5NPC1LMNAGAA | |
| SCHEMBL24879888 | 0.86 | KCNH2 (0.36) | KCNH2LMNAKMT2A | |
| SCHEMBL24879934 | 0.85 | TEAD1 (0.42) | WDR5 | |
| SCHEMBL24791425 | 0.83 | TEAD1 (0.40) | KCNH2 | |
| SCHEMBL24880123 | 0.80 | WDR5 (0.33) | WDR5NPC1LMNAGAARAB9A | |
| SCHEMBL24880208 | 0.76 | TRPV1 (0.33) | KCNH2 | |
| SCHEMBL24879914 | 0.76 | TEAD1 (0.44) | WDR5NPC1LMNAGAARAB9A | |
| SCHEMBL24879891 | 0.76 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL24880379 | 0.76 | TEAD1 (0.35) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |