SCHEMBL24880

SCHEMBL24880

CN1CC[C@]23c4c5ccc(OCc6ccccc6)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5

nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 8/20 0.74
▸ OPRM1 P35372 7/20 0.74
▸ OPRK1 P41145 5/20 0.74
▸ MRGPRX2 Q96LB1 4/20 0.74
▸ ADRB1 P08588 1/20 0.74
▸ PDE4D Q08499 1/20 0.74
▸ PDE3A Q14432 1/20 0.74
▸ SLC22A1 O15245 1/20 0.66
▸ ADRA2A P08913 1/20 0.66
▸ ARRB1 P49407 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278380 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL29359245 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL678993 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL15249248 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1MRGPRX2ADRB1
Hydrochloric Acid SCHEMBL31058090 0.99 OPRD1 (0.73) OPRD1OPRM1OPRK1MRGPRX2ADRB1
Propionic Acid SCHEMBL28993771 0.95 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL16866229 0.95 OPRM1 (0.66) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL23673341 0.91 OPRD1 (0.71) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL31298539 0.91 OPRM1 (0.76) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL27557540 0.90 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6956 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 — — EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 — — US claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 — — US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 — — US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 — — US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 — — EP claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 — — US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 — — EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 — — WO claimed
EP-0914097-A2 COMPOSITION AND DOSAGE FORM COMPRISING OPIOID ANTAGONIST ALZA CORPORATION (US) 1999-05-12 — — EP claimed
US-5866164-A Composition and dosage form comprising opioid antagonist ALZA CORPORATION (US) 1999-02-02 — — US claimed
EP-0785775-A4 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO CELTIQUE SA (LU) 1998-08-19 — — EP claimed
WO-1997033566-A2 COMPOSITION AND DOSAGE FORM COMPRISING OPIOID ANTAGONIST ALZA CORPORATION (US) 1997-09-18 — — WO claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 — — US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 — — EP claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 — — WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 — — EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 — — EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 — — US claimed
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