Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645498 | 0.81 | CYP19A1 (0.45) | PDE10ACYP19A1TSHRGRM5TYR | |
| SCHEMBL3868934 | 0.79 | SPNS2 (0.49) | TSHRSPNS2TDP1 | |
| SCHEMBL27867153 | 0.79 | SPNS2 (0.39) | CYP19A1SPNS2 | |
| SCHEMBL585669 | 0.78 | CYP19A1 (0.43) | CYP19A1TSHR | |
| SCHEMBL27850127 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 | |
| SCHEMBL27850152 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 | |
| SCHEMBL27850239 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 | |
| SCHEMBL27850112 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 | |
| SCHEMBL28794303 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 | |
| SCHEMBL27850106 | 0.76 | SPNS2 (0.46) | TSHRSPNS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |