Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435520 | 0.89 | CYP19A1 (0.41) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL27850120 | 0.88 | CYP19A1 (0.45) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL27867261 | 0.87 | CYP19A1 (0.40) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL9645498 | 0.84 | CYP19A1 (0.45) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL7907659 | 0.83 | RPS6KB1 (0.33) | CYP19A1ALDH1A1RPS6KB1GSK3B | |
| SCHEMBL16267964 | 0.81 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL14305754 | 0.81 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL6855316 | 0.79 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL585506 | 0.79 | — | — | |
| SCHEMBL24880321 | 0.78 | PDE10A (0.36) | CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244135-B | Resin composition containing fullerene derivative and preparation method thereof, resin coating film and enameled wire | 东袋株式会社 | 2024-08-16 | — | — | CN | disclosed |
| EP-3395848-B1 | POLYURETHANE, CURABLE COMPOSITION, OVERCOAT FILM, AND FLEXIBLE WIRING BOARD AND PRODUCTION METHOD THEREFORE | NIPPON POLYTECH CORP (JP) | 2024-02-28 | — | — | EP | disclosed |
| CN-107614619-B | Thermosetting material and cured product | 积水化学工业株式会社 | 2023-05-09 | — | — | CN | disclosed |
| CN-115244135-A | Method for producing fullerene derivative-containing resin composition, fullerene derivative-containing resin composition obtained thereby, resin coating material, resin coating film, and enameled wire | 东袋株式会社 | 2022-10-25 | — | — | CN | disclosed |
| EP-3395900-B1 | CURABLE COMPOSITION, CURED OBJECT, OVERCOAT FILM, COATED FLEXIBLE WIRING BOARD, AND PROCESS FOR PRODUCING SAME | NIPPON POLYTECH CORP (JP) | 2021-09-22 | — | — | EP | disclosed |
| US-11044807-B2 | Polyurethane, curable composition, overcoat film, and flexible wiring board and production method therefor | NIPPON POLYTECH CORP. (JP) | 2021-06-22 | — | — | US | disclosed |
| WO-2021005912-A1 | POLYURETHANE AND CURABLE COMPOSITION | 日本ポリテック株式会社 | 2021-01-14 | — | — | WO | disclosed |
| WO-2021005913-A1 | CURABLE COMPOSITION, CURED OBJECT, OVERCOAT FILM, AND FLEXIBLE WIRING BOARD AND PRODUCTION METHOD THEREFOR | 日本ポリテック株式会社 | 2021-01-14 | — | — | WO | disclosed |
| WO-2021005914-A1 | CURED OBJECT, OVERCOAT FILM, AND FLEXIBLE WIRING BOARD | 日本ポリテック株式会社 | 2021-01-14 | — | — | WO | disclosed |
| US-10889729-B2 | Curable composition, cured object, overcoat film, coated flexible wiring board, and process for producing same | NIPPON POLYTECH CORP. (JP) | 2021-01-12 | — | — | US | disclosed |
| US-20110253426-A1 | CURABLE COMPOSITION | SHOWA DENKO K.K. (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110257257-A1 | COMPOSITION FOR TREATMENT OF EPITHELIAL TISSUE | NOVODERMIX INTERNATIONAL LIMITED (VG) | 2011-10-20 | — | — | US | disclosed |
| US-20110136941-A1 | UNDERFILL FORMULATION AND METHOD OF INCREASING AN ADHESION PROPERTY OF SAME | SHEKHAWAT LINDA A | 2011-06-09 | — | — | US | disclosed |
| US-7926697-B2 | Underfill formulation and method of increasing an adhesion property of same | INTEL CORPORATION (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100093740-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-04-15 | — | — | US | disclosed |
| EP-2125823-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-12-02 | — | — | EP | disclosed |
| CN-101568542-A | 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-28 | — | — | CN | disclosed |
| US-20090076220-A1 | UNDERFILL FORMULATION AND METHOD OF INCREASING AN ADHESION PROPERTY OF SAME | INTEL CORPORATION | 2009-03-19 | — | — | US | disclosed |
| CN-101273417-A | Transparent conductive sheet for touch panel, method for manufacturing same, and touch panel | SHINETSU POLYMER CO (JP) | 2008-09-24 | — | — | CN | disclosed |
| WO-2008078291-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093740-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | HCRTR1, HCRTR2, NPY5R | CYP19A1 684/4885SMN1; SMN2 4400/4885TSHR 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.